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Study identifier: NCT06657534 Synced from ClinicalTrials.gov · July 29, 2026
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SISIPUSH: Evaluation of Hemolysis and Iatrogenic Anemia Using the Push-pull Method to Obtain Blood from Pediatric Patients with Central Venous Catheters

Condition: Pediatrics · Central Venous Catheter  ·  Sponsor: University Hospital, Ghent

PhaseNA
Planned participants150
Who can joinAll sexes, 0 Years to 18 Years
Healthy volunteersNo

About this study

Anemia is frequently observed during hospitalizations, both in adults and children. In addition to the fact that anemia can be caused by an acute or chronic condition, blood samples taken during the hospital stay contribute to additional blood loss (so-called iatrogenic anemia). For children, the relative amount of blood taken at each blood collection is greater than in adults. It is therefore expected that in children, due to the lower circulating blood volume, the relative impact of repeated blood sampling is greater and interventions such as sparing the number of blood samples or blood volume can have a relevant impact on the onset of anemia, the need for iron supplements or blood transfusions and the general clinical recovery. For children, only limited data are available on the development of iatrogenic anemia during hospital stay. In a study of children in an intensive care unit, a decrease in hemoglobin of 0.7 g/dl can already be seen with an average stay of 4.5 days (and an average number of blood samples of 2.9) (François et al. Ped Crit Car Med, 2022). The average blood volume lost to blood samples during the stay is 3.9 ml/kg, which already corresponds to 5% of the total blood volume. Interventions to decrease the frequency of blood sampling or to perform the same analyses on a smaller blood volume (e.g. adapted, smaller blood tubes for children) are therefore useful in preventing the development of anemia during a hospital stay, especially in children. Alternat…

This description comes directly from the study's public registry record.

Talk to the study team

Levi Hoste, MD, PhD  ·  +32 9 332 35 40  ·  levi.hoste@uzgent.be

Always discuss trial participation with your own doctor first.

Locations (1)

Ghent University HospitalGhent, BelgiumRecruiting

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Source record: clinicaltrials.gov/study/NCT06657534