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Study identifier: NCT06657222 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

First in Human Study of TUB-030 in Patients With Advanced Solid Tumors

Condition: Advanced Solid Tumors · HNSCC · SCLC  ·  Sponsor: Tubulis GmbH

PhasePhase 1/Phase 2
Planned participants250
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if the drug TUB-030 works to treat solid cancer in adults. The study will also explore the safety of TUB-030. The main questions it aims to answer are: To determine the safety and tolerability of TUB-030 To determine the maximum tolerated dose of TUB-030 as a single drug given to patients with solid cancer Researchers will also compare doses of TUB-030 in two specific cancer types, in patients with head and neck cancer and patients with non-small cell lung cancer, to see if TUB-030 works to treat these two solid cancer types and to determine the best dose. Participants will: Receive drug TUB-030 every 3 weeks Visit the clinic once every 3 weeks for checkups and tests Answer patient reported outcome questionnaires about their symptoms

This description comes directly from the study's public registry record.

Talk to the study team

Tubulis Clinical Trial Inquiries  ·  +491758005594  ·  ct-inquiries@tubulis.com

Always discuss trial participation with your own doctor first.

Locations (16)

Yale Cancer CenterNew Haven, Connecticut, United StatesRecruiting
University of MiamiMiami, Florida, United StatesRecruiting
Dana Farber Cancer InstituteBoston, Massachusetts, United StatesRecruiting
Mayo ClinicRochester, Minnesota, United StatesRecruiting
Washington UniversitySt Louis, Missouri, United StatesRecruiting
Mount SinaiNew York, New York, United StatesRecruiting
Cleveland ClinicCleveland, Ohio, United StatesRecruiting
Ohio State UniversityColumbus, Ohio, United StatesRecruiting
NEXT Oncology AustinAustin, Texas, United StatesRecruiting
NEXT Oncology - DallasIrving, Texas, United StatesRecruiting
NEXT Oncology - San AntonioSan Antonio, Texas, United StatesRecruiting
Fred Hutchinson Cancer CenterSeattle, Washington, United StatesRecruiting

+ 4 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06657222