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Study identifier: NCT06657209 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Normal-weight Diabetes: Adipocyte-directed Therapy With Pioglitazone or Tirzepatide

Condition: Diabetes Mellitus, Type 2 · Diabetes · Type 2 Diabetes  ·  Sponsor: Stanford University

PhasePhase 4
Planned participants104
Who can joinAll sexes, 30 Years to 70 Years
Healthy volunteersYes

About this study

This study is to investigate how adipocyte (fat cell) function and fat distribution differ between individuals with normal-weight type 2 diabetes (NWD), those with overweight type 2 diabetes (OWD), and normal-weight controls without diabetes (NWC). The study will assess whether adipocyte-directed therapies, specifically pioglitazone and tirzepatide, can improve insulin resistance, adipocyte function, and fat distribution in individuals with NWD. By analyzing the biological mechanisms underlying adipocyte dysfunction, the study aims to provide insights into novel treatment strategies for improving metabolic health in normal-weight individuals with type 2 diabetes.

This description comes directly from the study's public registry record.

Talk to the study team

Nina Shenoy, BS  ·  408-896-0134  ·  nshenoy8@stanford.edu

Alisa Turner, BS  ·  650-285-8855  ·  alturner@stanford.edu

Always discuss trial participation with your own doctor first.

Locations (2)

Stanford UniversityPalo Alto, California, United StatesRecruiting
Stanford University, Clinical and Translational Research Unit (CTRU)Stanford, California, United StatesNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06657209