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Study identifier: NCT06656988 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Contrast Medium Sparing Strategy Using Automated CO2 Injection During PVI for Prevention of Major Adverse Kidney Events (MAKE)

Condition: Peripheral Vascular Diseases · Kidney Diseases  ·  Sponsor: University of Leipzig

PhasePhase 3
Planned participants1960
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The primary objective of the trial is to evaluate if an iodinated contrast medium sparing strategy using automated Carbon Dioxide (CO2) Injection prevents Major Adverse Kidney Events up to 90 days (MAKE90) in patients at moderately elevated risk for contrast-associated acute kidney injury (CA-AKI) undergoing infrainguinal peripheral vascular interventions (PVI).

This description comes directly from the study's public registry record.

Talk to the study team

Sabine Steiner, Prof Dr  ·  +493419718770  ·  angiologie@medizin.uni-leipzig.de

Always discuss trial participation with your own doctor first.

Locations (11)

Tirol Kliniken InnsbruckInnsbruck, AustriaRecruiting
Universitätsklinik für Innere Medizin IIVienna, AustriaRecruiting
Kreiskrankenhaus AlsfeldAlsfeld, GermanyRecruiting
Universitäts-Herzzentrum Freiburg-Bad KrozingenBad Krozingen, GermanyRecruiting
Universitätsklinikum BonnBonn, GermanyNot Yet Recruiting
Klinikum Chemnitz gGmbHChemnitz, GermanyNot Yet Recruiting
DIAKO Krankenhaus gGmbH FlensburgFlensburg, GermanyNot Yet Recruiting
MVZ CCB Frankfurt und Main-Taunus GbRFrankfurt a.M., GermanyRecruiting
Universitätsklinikum LeipzigLeipzig, GermanyRecruiting
Klinikum rechts der Isar der Technischen Universität MünchenMünchen, GermanyRecruiting
GRN - Klinik WeinheimWeinheim, GermanyRecruiting

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Source record: clinicaltrials.gov/study/NCT06656988