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Study identifier: NCT06655883 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study of Suvorexant (MK-4305) for the Treatment of Insomnia Disorder in Participants With Opioid Use Disorder (MK-4305-098)

Condition: Insomnia  ·  Sponsor: Merck Sharp & Dohme LLC

PhasePhase 3
Planned participants300
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

People with opioid use disorder (OUD) can have trouble falling or staying asleep. Researchers want to know if suvorexant will help people with OUD fall asleep and stay asleep. The goal of this study is to learn about the safety of suvorexant and how well people tolerate it. Researchers also want to learn if suvorexant helps people sleep longer compared to people who take placebo. A placebo looks like the study medicine but has no actual study medicine in it.

This description comes directly from the study's public registry record.

Talk to the study team

Toll Free Number  ·  1-888-577-8839  ·  Trialsites@msd.com

Always discuss trial participation with your own doctor first.

Locations (11)

Yale University School of Medicine ( Site 1003)New Haven, Connecticut, United StatesRecruiting
CenExel iResearch, LLC ( Site 2010)Savannah, Georgia, United StatesRecruiting
Johns Hopkins University ( Site 1001)Baltimore, Maryland, United StatesRecruiting
Hassman Research Institute Marlton Site ( Site 2005)Marlton, New Jersey, United StatesRecruiting
The Rivus Wellness & Research Institute ( Site 2014)Oklahoma City, Oklahoma, United StatesRecruiting
Penn Medicine University of Pennsylvania Health System- Center for Studies of Addiction ( Site 1006)Philadelphia, Pennsylvania, United StatesRecruiting
Butler Hospital ( Site 1002)Providence, Rhode Island, United StatesRecruiting
Medical University of South Carolina ( Site 1005)Charleston, South Carolina, United StatesRecruiting
Adams Clinical Dallas ( Site 2007)DeSoto, Texas, United StatesRecruiting
Memorial Hermann Village ( Site 2001)Houston, Texas, United StatesRecruiting
VCU Institute for Drug and Alcohol Studies ( Site 1004)Richmond, Virginia, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06655883