Condition: HFpEF · LVDD · Myocardial Fibrosis · Sponsor: National Medical Research Center for Cardiology, Ministry of Health of Russian Federation
Patients with advanced heart failure with preserved ejection fraction (HFpEF) will be randomly assigned in open-label multicenter study to receive triple combination therapy with \[angiotensin receptor/neprilysin inhibitor \[ARNI\] + sodium-glucose cotransporter 2 inhibitor \[SGLTi\] + mineralocorticoid receptor antagonist \[MRA\]) or with individualized medical therapy \[SGLTi + renin-angiotensin system inhibitor \[RASi\] \[angiotensin receptor blocker \[ARB\] or angiotensin-converting enzyme inhibitor \[ACE-I\]), and will be treated for 52 weeks
This description comes directly from the study's public registry record.
Artem G Ovchinnikov, MD, PhD, DSc · +74954146612 · artcardio@mail.ru
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| National Medical Research Center for Cardiology, Ministry of Health of Russian Federation | Moscow, Russia | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06655480