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Study identifier: NCT06655155 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study to Assess the Efficacy and Safety of Efgartigimod PH20 SC in Adults With Systemic Sclerosis

Condition: Systemic Sclerosis (SSc)  ·  Sponsor: argenx

PhasePhase 2
Planned participants81
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The main purpose of this study is to evaluate the effect and safety of efgartigimod PH20 SC compared to placebo in adults with systemic sclerosis. The study consists of a screening period, a treatment period of up to 48 weeks and a safety follow-up period. After the screening period, eligible participants will be randomized in a 2:1 ratio to receive either efgartigimod PH20 SC or placebo. The total study duration can be up to approximately 15 months. More information can be found on: https://clinicaltrials.argenx.com/esscape

This description comes directly from the study's public registry record.

Talk to the study team

Sabine Coppieters, MD  ·  857-350-4834  ·  clinicaltrials@argenx.com

Always discuss trial participation with your own doctor first.

Locations (76)

Arizona Arthritis and Rheumatology AssociatesPhoenix, Arizona, United StatesRecruiting
UCLA Ronald Reagan University of California Los Angeles Medical CenterLos Angeles, California, United StatesRecruiting
IRIS Research and Development LLCPlantation, Florida, United StatesRecruiting
University of Illinois Health Outpatient Care CenterChicago, Illinois, United StatesRecruiting
DelRicht Research, LLCNew Orleans, Louisiana, United StatesRecruiting
Johns Hopkins Asthma and Allergy CenterBaltimore, Maryland, United StatesRecruiting
Thomas Jefferson UniversityColumbia, Maryland, United StatesRecruiting
University of Michigan HospitalAnn Arbor, Michigan, United StatesRecruiting
Perelman Center for Advanced MedicinePhiladelphia, Pennsylvania, United StatesRecruiting
Aprillus Asistencia e InvestigacionBuenos Aires, ArgentinaRecruiting
Instituto de Investigación Clínica TyTBuenos Aires, ArgentinaRecruiting
Consultorios Médicos Dr. Doreski - Fundacion RespirarBuenos Aires, ArgentinaRecruiting

+ 64 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06655155