Condition: Ameloblastoma · BRAF V600E Mutation Positive · Sponsor: Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
This study aims to evaluate the tumor shrinkage effect of preoperative targeted induction therapy with dabrafenib and trametinib in patients with conventional ameloblastoma harboring the BRAF V600E mutation. The study will assess the proportion of cases where mandibular continuity cannot be preserved that can be converted to cases where mandibular continuity is preserved, as well as the proportion of cases where complete resection is initially not feasible that become resectable.
This description comes directly from the study's public registry record.
ZHAO Zhang · +86 15150104115 · zaidezaidezz@hotmail.com
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| Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine | Shanghai, Shanghai Municipality, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06653517