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Study identifier: NCT06649539 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Delayed Dose Collagenase Clostridium Histolyticum (CCH) Protocol for Men With Peyronie's Disease

Condition: Peyronie Disease  ·  Sponsor: Charitable Union for the Research and Education of Peyronie's Disease

PhasePhase 4
Planned participants40
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Our team has previously demonstrated efficacy in performing a novel collagenase Clostridium histolyticum (CCH) injection protocol in men who previously failed to achieve a response to an initial 4 series of CCH. The objective of the current study is to evaluate a protocol that incorporates limited in-office modeling for up to 4 series, followed by up to 2 additional salvage series to determine safety and efficacy compared to historical data. Participants will receive up to 4 series of CCH injections using our previously published protocol, with mild in-office modeling. CCH injections are given on back-to back days, after which they are counseled to utilize Restorex and sildenafil daily, as instructed. Patients will undergo mild in-office modeling on day 2. The sexual partners of study participants will also be invited to enroll in the study and will complete non-validated questionnaires detailing their level of support for the patient's treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Landon Trost, MD  ·  801-655-0015  ·  email@mfp.clinic

Holli Burgon  ·  801-691-4714  ·  burgon.holli@menshealthstudies.com

Always discuss trial participation with your own doctor first.

Locations (1)

Male Fertility and Peyronie's ClinicOrem, Utah, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06649539