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Study identifier: NCT06648629 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Acceptance and Commitment Therapy for HIV+ Hazardous Drinkers

Condition: HIV-1-infection · Alcohol Drinking  ·  Sponsor: Syracuse University

PhaseNA
Planned participants300
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Alcohol consumption is a critical factor in HIV treatment that significantly contributes to poor treatment-related outcomes. Randomized clinical trials (RCTs) of alcohol interventions for people with HIV (PWH) have had limited success, perhaps due to an increasingly recognized co-morbitity of co-occurring hazardous alcohol use and other mental health-related problems among PWH. This has necessitated a shift in the literature towards trans-diagnostic approaches that target core psychological processes that underlie multiple mental health-related problems. One trans-diagnostic mechanism that is relevant to alcohol and other substance use is experiential avoidance (EA)- i.e., repeated, and maladaptive, use of substances and/or other behaviors to escape or avoid unwanted thoughts, feelings, and/or urges. Acceptance and commitment therapy (ACT) targets EA and is an empirically supported treatment for multiple psychological and behavioral health-related outcomes; however there have not been any full-scale RCTs of ACT for alcohol use among any population, including PWH. The investigators recently adapted a telephone-delivered ACT intervention originally developed for smoking cessation, into an intervention for PWH who drink at unhealthy levels (NIH/NIAAA; R34AA026246). This six-session, telephone-delivered ACT intervention for alcohol use showed high feasibility and acceptability in a pilot RCT conducted by our team. The overall objective of this application is therefore to determin…

This description comes directly from the study's public registry record.

Talk to the study team

Sarah E Woolf-King, PhD  ·  314-443-2354  ·  sewoolf@syr.edu

Stephen A Maisto, PhD  ·  samaisto@syr.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Syracuse UniversitySyracuse, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06648629