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Study identifier: NCT06645951 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Institution of an Italian Multicenter Database of Patients with Parathyroid Carcinoma or Atypical Parathyroid Adenoma

Condition: Parathyroid Gland Carcinoma · Parathyroid Gland Atypical Adenoma  ·  Sponsor: F.I.R.M.O. - Fondazione Italiana Ricerca sulle Malattie dell'Osso - Ente del Terzo Settore

PhaseN/A
Planned participants300
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

The goal of this observational study is to create, manage and analyze a multicenter national database of patients with parathyroid carcinoma or atypical parathyroid adenoma, aimed at collecting and studying anamnestic, diagnostic, genetic, clinical, histological, and therapeutic data in a relatively wide number of patients in Italy. The study will include 33 specialist clinical centers of endocrinology and endocrine surgery, located throughout the Italian territory, and to which patients refer from all the 20 regions of Italy. Data will be collected over time, both in retrospective and prospective manners, during the 10-year duration of the study, starting from the recruiting visit (basal visit) and then during each follow-up visits patients will undergo for the control of disease progression at the recruiting clinical centers. Collected data will include both the most classic traits of the pathology and the less common ones, with the final goal of refining and deepening medical knowledge in the field of these two extremely rare parathyroid cancers and be able to define optimal clinical and therapeutic management of patients, improving their quality and life expectancy. The main aspects this observational study aims to assess and clarify are: 1. Evaluation of prevalence and incidence of parathyroid carcinoma and atypical parathyroid adenoma in Italy, both as sporadic disease or in the context of genetic disorders. 2. Clinical, histological, and biochemical characterizati…

This description comes directly from the study's public registry record.

Talk to the study team

Maria Luisa Brandi, MD, PhD  ·  0039-055-2336663  ·  marialuisa@marialuisabrandi.it

Always discuss trial participation with your own doctor first.

Locations (33)

U.O.C. Endocrinologia, Azienda Ospedaliero Universitaria Policlinico Consorziale, Università degli Studi di Bari "Aldo Moro"Bari, ItalyNot Yet Recruiting
UOC Endocrinologia e Prevenzione e Cura del Diabete, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Dipartimento di Scienze Mediche e Chirurgiche (DIMEC), Alma Mater Studiorum Università di BolognaBologna, ItalyNot Yet Recruiting
Endocrinologia e Diabetologia, Azienda Ospedaliero-Universitaria di Cagliari, Presidio Ospedaliero Policlinico di MonserratoCagliari, ItalyNot Yet Recruiting
UO Endocrinologia e Malattie del Ricambio, Azienda Ospedaliero Universitaria di Ferrara, Sezione di Endocrinologia, Geriatria e Medicina Interna, Dipartimento di Scienze Mediche, Università degli Studi di FerraraFerrara, ItalyRecruiting
SOD Malattie del Metabolismo Minerale ed Osseo, Azienda Ospedaliero-Universitaria CareggiFlorence, ItalyRecruiting
Unità di Chirurgia Endocrina, Azienda Ospedaliero-Universitaria CareggiFlorence, ItalyNot Yet Recruiting
Ospedale Casa Sollievo della SofferenzaFoggia, ItalyNot Yet Recruiting
Clinica Endocrinologica, Dipartimento di Medicina Interna e Specialità Mediche (DiMI), IRCCS Ospedale Policlinico San Martino, Università di GenovaGenova, ItalyNot Yet Recruiting
Clinica Pediatrica ed Endocrinologia, IRCCS Ospedale Pediatrico Giannina GasliniGenova, ItalyNot Yet Recruiting
U.O.S.D. Centro Malattie Rare · Dipartimento di Pediatria IRCCS Ospedale Pediatrico Giannina GasliniGenova, ItalyNot Yet Recruiting
UOC di Endocrinologia, AOU Policlinico G. Martino, Dipartimento di Patologia Umana DETEV, Università di MessinMessina, ItalyNot Yet Recruiting
Dipartimento di Malattie Endocrino-Metaboliche, IRCCS Istituto Auxologico ItalianoMilan, ItalyNot Yet Recruiting

+ 21 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06645951