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Study identifier: NCT06645899 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Institution of an Italian Multicenter Database of Patients Affected by Hypoparathyroidism or Pseudohypoparathyroidism

Condition: Hypoparathyroidism · Pseudo Hypoparathyroidism  ·  Sponsor: F.I.R.M.O. - Fondazione Italiana Ricerca sulle Malattie dell'Osso - Ente del Terzo Settore

PhaseN/A
Planned participants600
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

The goal of this observational study is to create, manage and analyze a multicenter national database of patients affected by hypoparathyroidism or pseudohypoparathyroidism, aimed at collecting and studying anamnestic, diagnostic, genetic, clinical, and therapeutic data in a relatively wide number of patients with these two rare pathologies, in Italy. The study will include 41 specialist clinical centers of endocrinology, pediatric endocrinology, pediatrics, and endocrine surgery, located throughout the Italian territory, and to which patients refer from all the 20 regions of Italy. Data will be collected over time, both in retrospective and prospective manners, during the 10-year duration of the study, starting from the recruiting visit (basal visit) and then during each follow-up visits patients will undergo for the control of disease at the recruiting clinical centers. Collected data will include both the most classic traits of the pathology and the less common ones, with the final goal of refining and deepening medical knowledge in the field of these two clinical conditions affecting parathyroid function and calcium homeostasis, and, thus, to be able to define optimal clinical and therapeutic management of patients, improving their quality of life. The main aspects this observational study aims to assess and clarify are: 1. Evaluation of prevalence and incidence of hypoparathyroidism, globally and in its different etiological forms, and of pseudohypoparathyroidism in…

This description comes directly from the study's public registry record.

Talk to the study team

Maria Luisa Brandi, MD, PhD  ·  0039-055-2336663  ·  marialuisa@marialuisabrandi.it

Always discuss trial participation with your own doctor first.

Locations (41)

SC Pediatria e Pronto Soccorso Pediatrico - AOU SS. Antonio e Biagio e C. ArrigoAlessandria, ItalyNot Yet Recruiting
U.O.C. Endocrinologia, Azienda Ospedaliero Universitaria Policlinico Consorziale, Università degli Studi di Bari "Aldo Moro"Bari, ItalyNot Yet Recruiting
Unità di Pediatria, IRCCS Azienda Ospedaliero-Universitaria di BolognaBologna, ItalyNot Yet Recruiting
UOC Endocrinologia e Prevenzione e Cura del Diabete, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Dipartimento di Scienze Mediche e Chirurgiche (DIMEC), Alma Mater Studiorum Università di BolognaBologna, ItalyNot Yet Recruiting
Centro di Auxoendocrinologia e Genetica Medica della Clinica Pediatrica degli Spedali Civili di BresciaBrescia, ItalyNot Yet Recruiting
Endocrinologia e Diabetologia, Azienda Ospedaliero-Universitaria di Cagliari, Presidio Ospedaliero Policlinico di MonserratoCagliari, ItalyNot Yet Recruiting
UO Endocrinologia e Malattie del Ricambio, Azienda Ospedaliero Universitaria di Ferrara, Sezione di Endocrinologia, Geriatria e Medicina Interna, Dipartimento di Scienze Mediche, Università degli Studi di FerraraFerrara, ItalyRecruiting
Diabetologia e Endocrinologia, Auxoendocrinologia, Children's Hospital Meyer IRCCSFlorence, ItalyNot Yet Recruiting
SOD Malattie del Metabolismo Minerale ed Osseo, Azienda Ospedaliero-Universitaria CareggiFlorence, ItalyRecruiting
Ospedale Casa Sollievo della SofferenzaFoggia, ItalyNot Yet Recruiting
Centro di Alta Specialità in Osteoporosi Pediatrica e Malattie del Metabolismo Calcio-Fosforo, U.O.C. Clinica Pediatrica, Dipartimento di Scienze Pediatriche Generali e Specialistiche IRCCS Istituto Giannina GasliniGenova, ItalyNot Yet Recruiting
Clinica Endocrinologica, Dipartimento di Medicina Interna e Specialità Mediche (DiMI), IRCCS Ospedale Policlinico San Martino, Università di GenovaGenova, ItalyNot Yet Recruiting

+ 29 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06645899