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Study identifier: NCT06644781 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of Ifinatamab Deruxtecan in Subjects With Pretreated Advanced or Metastatic Esophageal Squamous Cell Carcinoma (ESCC) (IDeate-Esophageal01)

Condition: Esophageal Squamous Cell Carcinoma  ·  Sponsor: Daiichi Sankyo

PhasePhase 3
Planned participants510
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is designed to assess the efficacy and safety of ifinatamab deruxtecan (I-DXd) in patients with unresectable advanced or metastatic esophageal squamous cell carcinoma (ESCC) who have experienced disease progression following treatment with a platinum-based systemic therapy and an immune checkpoint inhibitor (ICI) compared with investigator's choice of chemotherapy (ICC).

This description comes directly from the study's public registry record.

Talk to the study team

Daiichi Sankyo Contact for Clinical Trial Information  ·  9089926400  ·  CTRinfo_us@daiichisankyo.com

Always discuss trial participation with your own doctor first.

Locations (88)

Providence Medical FoundationFullerton, California, United StatesRecruiting
Henry Ford Health SystemDetroit, Michigan, United StatesRecruiting
Baptist Cancer CenterMemphis, Tennessee, United StatesRecruiting
SCRI Oncology PartnersNashville, Tennessee, United StatesRecruiting
John Peter Smith HospitalFort Worth, Texas, United StatesRecruiting
Virginia Cancer SpecialistsFairfax, Virginia, United StatesRecruiting
Institut Jules BordetBrussels, BelgiumRecruiting
Cliniques Universitaires Saint-LucBrussels, BelgiumRecruiting
Antwerp University HospitalEdegem, BelgiumRecruiting
UZ LeuvenLeuven, BelgiumRecruiting
Anyang Cancer HospitalAnyang, ChinaRecruiting
Beijing Cancer HospitalBeijing, ChinaRecruiting

+ 76 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06644781