Condition: Familial Adenomatous Polyposis · Sponsor: University of Michigan Rogel Cancer Center
The purpose of this phase 1a/b trial is to find out what amount of exercise would be best to use for preventing recurrence of colorectal polyps. It involves following one of four different amounts of exercise regimens on a treadmill for 26 weeks. A treadmill will be placed in each study participant's home for the duration of the study. The exercise regimen will be personalized for each participant and monitored remotely by exercise personnel. The in-person study visits occur during the usual standard of care endoscopy exam and during a follow-up exam that is 26 weeks later. Small rectal tissue biopsies, about the size of a grain of rice, will be taken before and after 26 weeks of exercise. The study visits also involve questionnaires, a stool sample, and a blood sample. This study will inform the design of larger, future trials to investigate whether or not recurrence of polyps can be achieved with exercise.
This description comes directly from the study's public registry record.
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| University of Michigan Rogel Cancer Center | Ann Arbor, Michigan, United States | Recruiting |
| Cleveland Clinic Foundation | Cleveland, Ohio, United States | Not Yet Recruiting |
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Source record: clinicaltrials.gov/study/NCT06641310