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Study identifier: NCT06640166 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Encorafenib + Cetuximab Beyond Progression in Combination With FOLFIRI in Patients With BRAF V600E Mutated Metastatic Colorectal Cancer Progressing on Encorafenib + Cetuximab.

Condition: Colorectal Carcinoma · Colorectal Neoplasms · Colorectal Tumor  ·  Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS

PhasePhase 2
Planned participants25
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The aim of this study is to determine the activity of encorafenib plus cetuximab in combination with FOLFIRI in patients with BRAF V600E mutated metastatic colorectal cancer progressing on encorafenib plus cetuximab administered in second line.

This description comes directly from the study's public registry record.

Talk to the study team

Maria Alessandra Calegari  ·  +39 06 30156318  ·  mariaalessandra.calegari@policlinicogemelli.it

Maria Alessandra Calegari  ·  +39 06 30156318  ·  eclypsestudy@policlinicogemelli.it

Always discuss trial participation with your own doctor first.

Locations (3)

Fondazione IRCCS Istituto Nazionale dei TumoriMilan, ItalyNot Yet Recruiting
Fondazione Policlinico Universitario Agostino Gemelli, IRCCSRoma, ItalyRecruiting
Ospedale Cardinale G. PanicoTricase, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT06640166