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Study identifier: NCT06639464 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Semaglutide for Helping Opioid Recovery

Condition: Opioid Use Disorder  ·  Sponsor: Brigham and Women's Hospital

PhasePhase 2
Planned participants46
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The is a pilot, 12-week, double-blind, placebo-controlled, randomized trial of individuals with opioid use disorder (OUD) newly initiating buprenorphine to receive either weekly injections of semaglutide (n=23) or matching placebo (n=23). The primary aim is to determine the effects of semaglutide on cue-reactivity among individuals with OUD. The secondary aim is to assess the preliminary efficacy, safety, and tolerability of semaglutide for OUD.

This description comes directly from the study's public registry record.

Talk to the study team

Joji Suzuki  ·  617-732-5752  ·  jsuzuki2@bwh.harvard.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Brigham and Women's HospitalBoston, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06639464