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Study identifier: NCT06637436 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

PrEP Readiness Interventions for Sustained Motivation (PRISM)

Condition: HIV · Methamphetamine Disorders  ·  Sponsor: Florida International University

PhaseNA
Planned participants400
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a hybrid type I randomized controlled trial to test the effectiveness of contingency management (CM) alone versus CM with motivational interviewing (MI) for optimizing entry or re-entry into the HIV prevention or care continua. A total of 400 participants will be randomized to CM (n = 200) or MI+CM (n = 200), all delivered via telehealth. Monthly follow-up assessments will be completed over 12 months to examine effectiveness MI+CM for the primary outcome - filling a pre-exposure prophylaxis (PrEP) or anti-retroviral therapy (ART) prescription (verified using a digital photo). Secondary outcomes will include: self-reported PrEP or ART clinical evaluation by a provider; self-reported meth and other substance use severity (ASSIST), and self-reported receptive and insertive condomless anal sex (CAS).

This description comes directly from the study's public registry record.

Talk to the study team

Adam Carrico Professor, PhD  ·  305-348-7887  ·  acarrico@fiu.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Florida International UniversityMiami, Florida, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06637436