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Study identifier: NCT06637423 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Patients With Bladder Cancer (MK-2870-027)

Condition: Non-Muscle Invasive Bladder Cancer  ·  Sponsor: Merck Sharp & Dohme LLC

PhasePhase 1/Phase 2
Planned participants32
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of the study is to learn about the safety of Sacituzumab Tirumotecan and if people can tolerate it when given in the bladder and find the highest dose that people can take without having certain problems. Researchers will then choose a dose level of Sacituzumab Tirumotecan to use in future studies to learn how well the drug works.

This description comes directly from the study's public registry record.

Talk to the study team

Toll Free Number  ·  1-888-577-8839  ·  Trialsites@msd.com

Always discuss trial participation with your own doctor first.

Locations (13)

Michael G Oefelein Clinical Trials ( Site 0053)Bakersfield, California, United StatesRecruiting
Moffitt Cancer Center ( Site 0057)Tampa, Florida, United StatesRecruiting
Northwestern University ( Site 0051)Chicago, Illinois, United StatesRecruiting
Johns Hopkins University ( Site 0055)Baltimore, Maryland, United StatesRecruiting
Princess Margaret Cancer Centre ( Site 0003)Toronto, Ontario, CanadaRecruiting
Centre intégré universitaire de santé et de services sociaux de l'Estrie - Centre Hospitalier Univer ( Site 0002)Sherbrooke, Quebec, CanadaRecruiting
Hôpital Claude Huriez ( Site 0012)Lille, Nord, FranceActive Not Recruiting
HENRI MONDOR HOSPITAL ( Site 0011)Créteil, Val-de-Marne, FranceActive Not Recruiting
Gustave Roussy ( Site 0013)Villejuif, Val-de-Marne, FranceActive Not Recruiting
Erasmus Medisch Centrum ( Site 0032)Rotterdam, South Holland, NetherlandsRecruiting
Hospital Universitario Virgen de la Victoria ( Site 0043)Málaga, Andalusia, SpainRecruiting
Hospital Universitario 12 de Octubre ( Site 0042)Madrid, SpainRecruiting

+ 1 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06637423