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Study identifier: NCT06636552 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

An Investigator-Initiated, Phase II, Multicenter, Open-Label, Single-Arm, Prospective Clinical Trial to Evaluate the Efficacy and Safety of Alternating Bortezomib-Based Regimens in Combination With DaratUMumab Followed by Maintenance With Daratumumab in the Frontline Setting of Primary Plasma CEll L

Condition: Primary Plasma Cell Leukemia  ·  Sponsor: Hellenic Society of Hematology

PhasePhase 2
Planned participants43
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

The primary objective of this study is to evaluate the efficacy of the alternating D-PAD/D-CVD induction regimen followed by D-CVD consolidation regimen and maintenance with daratumumab monotherapy, in terms of PFS, in the first-line setting of pPCL.

This description comes directly from the study's public registry record.

Talk to the study team

Eirini Katodritou, Dr  ·  +302313301173  ·  eirinikatodritou@gmail.com

Marina Stogianni  ·  0030 2107211806  ·  info@eae.gr

Always discuss trial participation with your own doctor first.

Locations (7)

1st Propaedeutic Department, "Laiko" General Hospital of AthensAthens, Attica, GreeceRecruiting
Hematology Clinic, General Hospital of Athens "Evanggelismos"Athens, Attica, GreeceRecruiting
Hematology Department "Alexandra" General Hospital of AthensAthens, Attica, GreeceRecruiting
Hematology Department, University General Hospital of AlexandroupolisAlexandroupoli, Evros, GreeceRecruiting
Hematology Department, Regional General Hospital for Cancer Treatment "Metaxa" of PiraeusPiraeus, GreeceRecruiting
Hematology Department, General Hospital of Thessaloniki "Papanikolaou"Thessaloniki, GreeceRecruiting
Hematology Department, Theageneion Cancer HospitalThessaloniki, GreeceRecruiting

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Source record: clinicaltrials.gov/study/NCT06636552