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Study identifier: NCT06636435 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Phase I, First in Human Study of CBA-1205, Anti-DLK1 Monoclonal Antibody in Patients With Advanced Solid Tumors, Hepatocellular Carcinoma (HCC), Melanoma, and Pediatric Cancer

Condition: Solid Tumors · Hepatocellular Carcinoma (HCC) · Malignant Melanoma  ·  Sponsor: Chiome Bioscience Inc.

PhasePhase 1
Planned participants66
Who can joinAll sexes, 2 Years to no upper limit
Healthy volunteersNo

About this study

In this first-in-human, muticenter, non-randomized, open-label, standard 3+3 dose escalation Phase I study encompasses 5 parts (Part 1-5). The purpose of this FIH study is to evaluate the safety and tolerability profile of CBA-1205.

This description comes directly from the study's public registry record.

Talk to the study team

Tanaka Miseri Chiome Bioscience Inc.  ·  +81-3-6383-3561  ·  ir@chiome.co.jp

General Affairs and Human Resources Department Chiome Bioscience Inc.  ·  +81-3-6383-3561

Always discuss trial participation with your own doctor first.

Locations (5)

National Cancer Center Hospital EastKashiwa, Chiba, JapanRecruiting
Kanagawa Cancer CenterYokohama, Kanagawa, JapanRecruiting
Niigata University Medical and Dental HospitalNiigata, Niigata, JapanRecruiting
National Cancer Center HospitalChūō, Tokyo, JapanRecruiting
University of Yamanashi HospitalChūō, Yamanashi, JapanRecruiting

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Source record: clinicaltrials.gov/study/NCT06636435