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Study identifier: NCT06634589 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study to Investigate Safety and Effectiveness of BGB-16673 in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignancies

Condition: B-cell Malignancy · Relapsed Cancer · Refractory Cancer  ·  Sponsor: BeOne Medicines

PhasePhase 1/Phase 2
Planned participants80
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to measure the safety, preliminary antitumor activity, pharmacokinetics, and pharmacodynamics with BGB-16673 in combination with other agents in participants with relapsed or refractory (R/R) B-cell malignancies. This study is structured as a master protocol with separate substudies. This study currently includes four substudies, and more substudies may be added as other combination agents are identified.

This description comes directly from the study's public registry record.

Talk to the study team

Study Director  ·  1.877.828.5568  ·  clinicaltrials@beonemed.com

Always discuss trial participation with your own doctor first.

Locations (50)

Mayo Clinic PhoenixPhoenix, Arizona, United StatesRecruiting
University of Southern California Norris ComprehensiveLos Angeles, California, United StatesRecruiting
Mayo Clinic JacksonvilleJacksonville, Florida, United StatesRecruiting
Moffitt Cancer CenterTampa, Florida, United StatesRecruiting
The University of Kansas Cancer CenterWestwood, Kansas, United StatesRecruiting
Mayo Clinic RochesterRochester, Minnesota, United StatesRecruiting
Washington University School of MedicineSt Louis, Missouri, United StatesRecruiting
Summit Medical GroupFlorham Park, New Jersey, United StatesRecruiting
Icahn School of Medicine At Mount SinaiNew York, New York, United StatesRecruiting
Columbia University Medical CenterNew York, New York, United StatesRecruiting
Weill Cornell Medical College Newyork Presbyterian HospitalNew York, New York, United StatesRecruiting
Memorial Sloan Kettering Cancer Center MskccNew York, New York, United StatesRecruiting

+ 38 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06634589