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Study identifier: NCT06634472 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Artificial Intelligence-Enabled Skin Perforator Segmentation

Condition: Microvascular Free Flap Transfer · Fibula Flap  ·  Sponsor: The University of Hong Kong

PhaseN/A
Planned participants49
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Computer-assisted surgery has revolutionized reconstruction with more efficient, accurate, and predictable surgery, as reported in our previous studies. Skin perforators are vessels that travel through muscles and septa to supply the skin. The identification of skin perforators is crucial for a safe fibula osteocutaneous free flap harvest with computer-assisted surgery. Different methods have been proposed in the past, each of which has its own limitations. Traditionally, skin perforators are identified with a Doppler ultrasound. Berrone et al. measured the locations with a Doppler ultrasound and imported the information back to guide virtual surgical planning. However, their study showed imprecise concordance between handheld Doppler measurements and the actual perforator locations; good correlation between the location of perforators and bone segments was identified in only four out of six cases investigated. To improve on the accuracy, computed tomography angiography was used for skin perforator identification. Battaglia et al. manually marked the perforating vessel location at the subcutaneous level and reported good correlation. However, the manual segmentation of the perforator was at the subcutaneous level only. The course of the perforators, which would be more significant for the design of computer-assisted fibula osteocutaneous free flap harvest, was not shown. To incorporate the course of skin perforators into fibula osteocutaneous free flap virtual surgical plan…

This description comes directly from the study's public registry record.

Talk to the study team

Jane J PU, MDS  ·  852-28590534  ·  drjanepu@hku.hk

Yuxiong Su, PhD  ·  852-28590534  ·  richsu@hku.hk

Always discuss trial participation with your own doctor first.

Locations (1)

The University of Hong KongHong Kong, Hong KongRecruiting

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Source record: clinicaltrials.gov/study/NCT06634472