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Study identifier: NCT06634394 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

APVO436 Phase 1b/2 Study in Patients With Newly Diagnosed AML

Condition: Acute Myeloid Leukemia (AML)  ·  Sponsor: Aptevo Therapeutics

PhasePhase 1
Planned participants39
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

A multi-center, open-label, dose-finding study of five dose levels of APVO436 in combination with venetoclax and azacitidine (ven/aza) in adult patients with newly diagnosed, CD123+ AML.

This description comes directly from the study's public registry record.

Talk to the study team

Caroline Taromino  ·  7735749572  ·  tarominoC@apvo.com

Always discuss trial participation with your own doctor first.

Locations (7)

Colorado Blood Cancer InstituteDenver, Colorado, United StatesRecruiting
University of MiamiMiami, Florida, United StatesRecruiting
University of KansasFairway, Kansas, United StatesRecruiting
Gabrail Cancer CenterCanton, Ohio, United StatesRecruiting
Oncology Hematology CareCincinnati, Ohio, United StatesRecruiting
University of Texas Southwestern Medical CenterDallas, Texas, United StatesRecruiting
MD Anderson Cancer CenterHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06634394