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Study identifier: NCT06632587 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Timing Impact of Early vs. Late Cranioplasty on Hemicraniectomy Outcomes

Condition: Craniocerebral Trauma · Stroke · Intracranial Hemorrhages  ·  Sponsor: Thomas Jefferson University

PhaseNA
Planned participants44
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

This prospective, randomized study aims to comprehensively evaluate the impact of cranioplasty timing on postoperative complications and long-term functional outcomes following decompressive hemicraniectomy (DHC). The primary endpoint focuses on comparing the rates of various postoperative complications, including infection, seizures, return to the operating room, and the need for ventriculoperitoneal shunting, between patients undergoing standard of care cranioplasty (\>3 months after DHC) and those receiving early cranioplasty (within 8 weeks).

This description comes directly from the study's public registry record.

Talk to the study team

Pious Patel, MD  ·  (215) 955-7000  ·  pious.patel@jefferson.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Thomas Jefferson University HospitalsPhiladelphia, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06632587