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Study identifier: NCT06631534 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Effect of Dexmedetomidine Supplementation to General Anaesthesia in Paediatric Transcatheter Closure of Atrial Septal Defect

Condition: Atrial Septal Defect (ASD) · Dexmedetomidine · Delirium - Postoperative  ·  Sponsor: Alexandria University

PhasePhase 4
Planned participants30
Who can joinAll sexes, 3 Years to 12 Years
Healthy volunteersNo

About this study

The aim of this randomized trial is to determine efficacy of dexmedetomidine in improving quality of recovery in pediatric patients undergoing interventional catheter closure of ASD while maintaining the hemodynamic parameters. Additionally he stress reducing effects of dexmedetomidine will be investigated in this population . The main questions it aims to answer are: Does Dexmedetomidine maintain stable hemodynamics in pediatric patients undergoing transcatheter ASD Closure while improving their quality of recovery? Does dexmedetomidine prolong duration of recovery and time to extubation in pediatric patients ? Does dexmedetomidine exert stress reducing properties in this population? Participants will: Either be administered Dexmedetomidine in a loading/maintenance regimen or a placebo, with hemodynamics being monitored at the baseline, intraoperatively and postoperatively, with recovery time and quality of recovery especially emergence delirium being monitored. Stress hormone levels will be sampled at baseline and postoperatively.

This description comes directly from the study's public registry record.

Talk to the study team

Mohamed Okasha, Specialist - MSc  ·  0201006462352  ·  m_adel13@alexmed.edu.eg

Always discuss trial participation with your own doctor first.

Locations (1)

Alexandria University Hospitals - SemouhaAlexandria, Alexandria Governorate, EgyptRecruiting

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Source record: clinicaltrials.gov/study/NCT06631534