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Study identifier: NCT06629779 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.

Condition: Metastatic Castration-Resistant Prostate Cancer  ·  Sponsor: Pfizer

PhasePhase 3
Planned participants900
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study will explore whether a combination of the investigational drug PF-06821497 and enzalutamide will work better than taking enzalutamide alone in participants with mCRPC who are ARSi or abiraterone naïve.

This description comes directly from the study's public registry record.

Talk to the study team

Pfizer CT.gov Call Center  ·  1-800-718-1021  ·  ClinicalTrials.gov_Inquiries@pfizer.com

Always discuss trial participation with your own doctor first.

Locations (240)

Ironwood Cancer & Research CentersChandler, Arizona, United StatesRecruiting
Ironwood Cancer & Research CentersGilbert, Arizona, United StatesRecruiting
Palo Verde Hematology OncologyGlendale, Arizona, United StatesRecruiting
Ironwood Cancer & Research CentersGlendale, Arizona, United StatesRecruiting
Ironwood Cancer & Research CentersGoodyear, Arizona, United StatesRecruiting
Ironwood Cancer & Research CentersMesa, Arizona, United StatesRecruiting
Ironwood Cancer & Research CentersMesa, Arizona, United StatesRecruiting
Ironwood Cancer & Research CentersPhoenix, Arizona, United StatesRecruiting
Ironwood Cancer & Research CentersScottsdale, Arizona, United StatesRecruiting
Highlands OncologyFayetteville, Arkansas, United StatesRecruiting
Arkansas Urology - Little RockLittle Rock, Arkansas, United StatesRecruiting
Highlands OncologyRogers, Arkansas, United StatesRecruiting

+ 228 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06629779