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Study identifier: NCT06629064 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Cognitive Control Training for Extinction in PTSD

Condition: Post-Traumatic Stress Disorders · Stress Disorders, Traumatic · Post Traumatic Stress Disorder  ·  Sponsor: VA Office of Research and Development

PhaseNA
Planned participants120
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

The proposed study will test whether a working memory training (WMT) program improves fear extinction learning and its underlying neural circuitry in Veterans with posttraumatic stress disorder (PTSD). WMT is designed to improves the ability to maintain task-relevant information in mind. The project will further validate the relationship between working memory and fear extinction using novel computational and multivariate analyses that link to specific PTSD symptoms. If WMT can enhance fear extinction learning, then WMT may be a powerful adjunctive treatment that can enhance exposure therapy outcomes or be leveraged as a stand-alone treatment. This project supports the Department of Veteran Affairs mission of developing viable targets of treatment for Veterans with PTSD.

This description comes directly from the study's public registry record.

Talk to the study team

Daniel M Stout, PhD  ·  (858) 642-3944  ·  Daniel.Stout@va.gov

Always discuss trial participation with your own doctor first.

Locations (1)

VA San Diego Healthcare System, San Diego, CASan Diego, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06629064