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Study identifier: NCT06627894 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Attenuating DEPression With Internet CBT to Slow Cognitive Decline in Older ICU Survivors(ADEPT-ICU)

Condition: Depression · Cognitive Decline  ·  Sponsor: Indiana University

PhaseNA
Planned participants300
Who can joinAll sexes, 50 Years to no upper limit
Healthy volunteersNo

About this study

Depression affects one-third of intensive care unit (ICU) survivors and represents a potentially modifiable target to slow cognitive decline and reduce the risk of Alzheimer's disease and related dementias (ADRD). Our multi-PI team proposes a two-arm RCT called ADEPT-ICU (Attenuating DEPression with Internet CBT to Slow Cognitive Decline in Older ICU Survivors), which will test the efficacy of an internet CBT intervention called Good Days Ahead (GDA) to reduce the burden of subjective cognitive decline (SCD) in older ICU survivors with moderate to severe depressive symptoms after ICU hospitalization.

This description comes directly from the study's public registry record.

Talk to the study team

Babar Khan, MD, MS  ·  317-274-9132  ·  bakhan@iu.edu

Lori Rawlings, RN, BSN  ·  317-274-9052  ·  rawlingl@regenstrief.org

Always discuss trial participation with your own doctor first.

Locations (2)

Eskenazi HospitalIndianapolis, Indiana, United StatesRecruiting
IU Health Methodist HospitalIndianapolis, Indiana, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06627894