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Study identifier: NCT06627036 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Dermoscopy vs Standard Marking for the Completeness of Excision of Keratinocyte Skin Cancers: The ClearMark Trial

Condition: Keratinocyte Skin Cancer  ·  Sponsor: Hull University Teaching Hospitals NHS Trust

PhasePhase 4
Planned participants1376
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

What is the study about? This study aims to improve the success rate of removal surgery for a common type of skin cancer. We will compare two different methods of marking (drawing where to remove) the skin before removing the lump: the normal method using magnifying glasses and theatre lights, and our proposed method using a handheld magnifying device called a dermatoscope. Why is this study important? Skin cancer is the most common cancer in the UK. Currently, up to 10-11% of surgeries do not remove all of the cancer, which means patients may need more treatment. We do not know whether using a dermatoscope can help surgeons remove all of the cancer more often or not. If it does, it could prevent patients needing more surgery or time in hospital. What will happen during the study? A computer will randomly allocate each participant to marking using the normal method, or using a dermatoscope. The surgery will then proceed as usual. After the surgery, patients will be asked to fill in a simple questionnaire about their thoughts. We will collect data from patients' notes to monitor the success of the surgery and any more treatments needed. What will we measure? We will check participants records to see if the cancer was entirely removed. This is reported by a pathologist whenever a skin lump or bump is removed. In time, we will also look at 5-year recurrence of cancer, the need for additional treatments, any problems from the marking process, how happy patients are with the pr…

This description comes directly from the study's public registry record.

Talk to the study team

Christos Vosinakis  ·  01482622185  ·  hyp-tr.hullplasticsresearch@nhs.net

Always discuss trial participation with your own doctor first.

Locations (1)

Castle Hill HospitalHull, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT06627036