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Study identifier: NCT06626737 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Dapagliflozin in Allo-HCT for aGVHD

Condition: Graft-versus-host Disease (GVHD)  ·  Sponsor: The First Affiliated Hospital of Soochow University

PhasePhase 2
Planned participants72
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if Dapagliflozin could prevent acute graft-versus-host disease (aGVHD) in patients undergoing allogeneic hematopoietic cell transplantation (allo-HCT) with haploidentical or unrelated donor and to assess its safety. The main questions it aims to answer are: Dose Dapagliflozin lower the cumulative incidence of aGVHD? What medical problems do participants undergoing allo-HCT from haploidentical or unrelated donor have when taking Dapagliflozin? Researchers will document the occurrence of graft-versus-host disease, hematopoietic reconstitution, survival rates and adverse effects. Participants will take Dapagliflozin every day in -1 to 14 days.

This description comes directly from the study's public registry record.

Talk to the study team

Yang XU  ·  86-0512-67781850  ·  xuyang1020@126.com

Biqi ZHOU  ·  86-0512-67781856  ·  zbq0903@126.com

Always discuss trial participation with your own doctor first.

Locations (1)

The First Affiliated Hospital of Soochow UniversitySuzhou, Jiangsu, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06626737