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Study identifier: NCT06626516 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Tebentafusp-tebn With LDT in Metastatic UM

Condition: Metastatic Uveal Melanoma  ·  Sponsor: Thomas Jefferson University

PhasePhase 1/Phase 2
Planned participants109
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is a multicenter, open label phase I/ II trial to assess the safety and clinical efficacy of tebentafusp-tebn in combination with liver-directed therapies in HLA-A\*0201 positive patients with metastatic uveal melanoma. In Part 1 of the study, the Prinicipal Investigator will investigate the safety and efficacy of tebentafusp-tebn in combination with hepatic IE in patients with a low to moderate hepatic disease burden. In Part 2, the study will investigate the efficacy of tebentafusp-tebn in combination with TACE in patients with bulky hepatic disease.

This description comes directly from the study's public registry record.

Talk to the study team

Site Public Contact  ·  215-600-9151  ·  ONCTrialNow@jefferson.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Thomas Jefferson UniversityPhiladelphia, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06626516