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Study identifier: NCT06626334 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Blue Light as an Anti-inflammatory and Analgesic Strategy in Thoracic Trauma

Condition: Rib Fractures · Pain, Acute  ·  Sponsor: Rebecca E Kotcher, MD

PhaseNA
Planned participants75
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The main goal of this clinical trial is to learn if light therapy improves pain and inflammation in adults with painful rib fractures. The main question it aims to answer is: \- Does bright blue light therapy in addition to standard pain treatments improve pain with breathing in adults with painful rib fractures? Researchers will compare participants who receive bright blue light therapy to participants who receive white light therapy and participants who receive only usual lighting conditions to look for differences in their pain control. In addition to their assigned light treatment, all participants will receive standard pain control treatments. Participants will be assigned randomly to one of three groups: one-third will be assigned to bright blue light therapy, one-third will be assigned to bright white light therapy, and one-third will be assigned to usual light only. They will receive their assigned light treatment for 4 hours during the morning/early afternoon for up to 3 days while they are in the hospital. On each day they receive the light treatment and on the day after their final light treatment: * They will be asked twice to rate their pain at rest and with taking a deep breath. * They will be tested to confirm that they are not experiencing delirium, or confusion related to being in the hospital. * Blood samples will be collected to look for changes in inflammation and the circadian clock, the body's natural 24-hour cycle.

This description comes directly from the study's public registry record.

Talk to the study team

Rebecca E Kotcher, MD  ·  412-647-7243  ·  kotcherre@upmc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Presbyterian Hospital, University of Pittsburgh Medical CenterPittsburgh, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06626334