Condition: Episodic Migraine · Chronic Migraine · Sponsor: Ipsen
A migraine is a headache with severe throbbing pain or a pulsating sensation, usually on one side of the head. It is often accompanied by feeling or being sick and a sensitivity to bright lights and sound. Migraines are caused by a series of events when the brain gets stimulated or activated, which causes the release of chemicals that cause pain. Corabotase (also known as IPN10200) is a medication that stops the release of these chemical messengers. Participants with episodic migraine (EM) or chronic migraine (CM) will be included in both Step 1 and Step 2. "Headache days" are when participants experience headaches that meet the criteria for a migraine or a headache without the additional migraine-specific symptoms. "Migraine days" occur when the headache displays clear migraine characteristics. This study aims to determine: * The safety and efficacy of injecting Corabotase directly into the muscles of the head and neck to prevent EM and CM, * The right amount (dose) of Corabotase to inject at each point, * The total amount (dose) of Corabotase that provides the best balance between safety and efficacy preventing migraines. Participants will need to complete a daily electronic migraine Diary (eDiary) and questionnaires throughout the study. The total study duration for a participant will be up to 44 weeks.
This description comes directly from the study's public registry record.
Ipsen Clinical Study Enquiries · See e mail · clinical.trials@ipsen.com
Always discuss trial participation with your own doctor first.
| Central Research Associates | Birmingham, Alabama, United States | Not Yet Recruiting |
| Rehabilitation & Neurological Services, LLC | Huntsville, Alabama, United States | Recruiting |
| MD First Research - Chandler - Neurology | Chandler, Arizona, United States | Recruiting |
| MD First Research - Chandler | Chandler, Arizona, United States | Recruiting |
| Baptist Health Center for Clinical Research | Little Rock, Arkansas, United States | Withdrawn |
| Axiom Research, LLC | Apple Valley, California, United States | Not Yet Recruiting |
| Profound Research. LLC - NCSC | Carlsbad, California, United States | Recruiting |
| M3Wake -PRI Encino | Encino, California, United States | Recruiting |
| WR-PRI Encino | Encino, California, United States | Recruiting |
| Neuro-Pain Medical Center | Fresno, California, United States | Recruiting |
| Fullerton Neurological Center - Neurology | Fullerton, California, United States | Recruiting |
| Neurology Center of North Orange County | Fullerton, California, United States | Not Yet Recruiting |
+ 154 more locations — full list on the registry record.
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT06625060