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Study identifier: NCT06623656 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Preoperative Radioimmunotherapy Versus Chemoimmunotherapy in NSCLC

Condition: Carcinoma, Non-Small-Cell Lung  ·  Sponsor: Weill Medical College of Cornell University

PhasePhase 2
Planned participants112
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if Cemiplimab with chemotherapy or Cemiplimab with stereotactic body radiation therapy (SBRT) works as treatment for stages IB, II, and III (N2) Non-Small Cell Lung Cancer (NSCLC). Before surgery to remove their lung cancer, participants will take: 1. Cemiplimab with chemotherapy (Arm A) every 3 weeks for up to 3 doses, OR 2. Cemiplimab every 3 weeks for up to 3 doses with SBRT (Arm B). SBRT will be given on day 1 before taking cemiplimab, then SBRT alone on day 2 and day 3. Four to 12 weeks following surgery, participants in both Arm A and Arm B will receive treatment with cemiplimab for one year.

This description comes directly from the study's public registry record.

Talk to the study team

Julissa Murillo  ·  2127463328  ·  jum4020@med.cornell.edu

Julia Muuse  ·  212-746-4528  ·  jum4029@med.cornell.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Weill Cornell MedicineNew York, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06623656