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Study identifier: NCT06623357 Synced from ClinicalTrials.gov · July 29, 2026
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Pilot Test of Caregiver Training Protocol for Brachial Plexus Birth Injury

Condition: Brachial Plexus Birth Palsy · Erbs Palsy  ·  Sponsor: Hugo W. Moser Research Institute at Kennedy Krieger, Inc.

PhaseNA
Planned participants20
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The brachial plexus is a network of nerves that exit the spinal cord from the C5-T1 nerve roots and provide all motor and sensory function to the arm from the shoulder to the fingers. Injury to the brachial plexus due to traction forces during labor and/or delivery causing the nerves to stretch or tear occurs in 0.9 out of 1000 live births. As many as 30% of infants with brachial plexus birth injury (BPBI) have paralysis or weakness in one arm resulting in lifelong impairment in arm function with joint contractures, the shortening of tendons, ligaments and muscles, leading to reduced range of motion (ROM), being a common complication and major source of disability. A primary goal of early management of BPBI is to use passive range of motion (PROM) (stretching) to improve and/or maintaining shoulder ROM due to the known risk of shoulder contracture within the first year of life. Infants who develop contractures face challenges in overall sensory-motor development and are less able to participate in meaningful occupations and activities of daily living due to limited upper extremity ROM. They are also at risk for subsequent surgeries throughout their lives. Occupational therapy practitioners (OTPs) and physicians who specialize in treating infants with BPBI recommend caregivers to perform PROM at every diaper change, which is every 1-3 hours in the first months of life, and every 4-6 hours by age one. A survey study by one of the investigators on this proposed project found tha…

This description comes directly from the study's public registry record.

Talk to the study team

Jennifer Wingrat, ScD, OTR/L  ·  4109679043  ·  wingrat@kennedykrieger.org

Always discuss trial participation with your own doctor first.

Locations (2)

Johns Hopkins All Children's HospitalSt. Petersburg, Florida, United StatesRecruiting
Kennedy Krieger InstituteBaltimore, Maryland, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06623357