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Study identifier: NCT06623110 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Phase II Study of RP2 as Immunoprevention in High-Risk Oral Precancerous Disease

Condition: High-Risk Oral Precancerous Disease  ·  Sponsor: Glenn J. Hanna

PhasePhase 2
Planned participants25
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this study is to understand the safety, tolerability, and potential efficacy of an injected immune therapy called RP2 to treat oral precancer conditions and prevent progression to an oral cancer. The name of the study drug involved in this study is: -RP2 (a genetically modified live Herpes Simplex V-1 strain)

This description comes directly from the study's public registry record.

Talk to the study team

Glenn Hanna, MD  ·  617-632-3090  ·  glenn_hanna@dfci.harvard.edu

Always discuss trial participation with your own doctor first.

Locations (2)

Brigham and Women's HospitalBoston, Massachusetts, United StatesRecruiting
Dana-Farber Cancer InstituteBoston, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06623110