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Study identifier: NCT06622486 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

First-in-human Trial of EGL-001 in Patients with Selected Advanced And/or Metastatic Solid Tumors

Condition: Solid Tumor, Adult  ·  Sponsor: Egle Therapeutics

PhasePhase 1/Phase 2
Planned participants50
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This multicenter, open-label, first-in-human, Phase 1/2 study consists of a Part 1 (Phase 1) open-label dose escalation of EGL-001 administered as a single agent and in combination with an anti-PD(L)-1 treatment, followed by a Part 2 (Phase 2) open-label dose expansion of EGL-001 administered at the RP2D in patients with recurrent and/or metastatic solid tumors as monotherapy and/or combination therapy with anti-PD(L)-1.

This description comes directly from the study's public registry record.

Talk to the study team

Pejvack Motlagh, MD  ·  33660462343  ·  contact@egle-tx.com

Always discuss trial participation with your own doctor first.

Locations (8)

Centr Georges Francois LeclercDijon, FranceNot Yet Recruiting
Institut Regional Du Cancer De MontpellierMontpellier, FranceRecruiting
Institut CurieParis, FranceRecruiting
Institut Gustave RoussyParis, FranceNot Yet Recruiting
Hospital Universitari Vall D HebronBarcelona, SpainNot Yet Recruiting
Hospital Universitario Fundacion Jimenez DiazMadrid, SpainNot Yet Recruiting
Clinica Universidad De NavarraPamplona, SpainNot Yet Recruiting
Hospital Clinico Universitario De ValenciaValencia, SpainRecruiting

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Source record: clinicaltrials.gov/study/NCT06622486