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Study identifier: NCT06620705 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Left Bundle Branch Area Pacing or Biventricular Pacing in AF and Left Ventricular Dysfunction

Condition: Heart Failure · Block, Heart · Pacing-Induced Cardiomyopathy  ·  Sponsor: srdpiers

PhaseNA
Planned participants34
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

It is unknown whether left bundle branch area pacing (LBBAP) or biventricular pacing best prevents or reverses left ventricular (LV) adverse remodelling in patients with atrial fibrillation (AF) who require ventricular pacing or CRT. This randomized non-inferiority cross-over trial will compare left ventricular end-systolic volume change and secondary endpoints between LBBAP and biventricular pacing in patients with AF and LV dysfunction.

This description comes directly from the study's public registry record.

Talk to the study team

Sebastiaan RD Piers, MD, PhD  ·  +31715262020  ·  s.r.d.piers@lumc.nl

Always discuss trial participation with your own doctor first.

Locations (2)

Aarhus University HospitalAarhus N, Aarhus N, DenmarkNot Yet Recruiting
Leiden University Medical CenterLeiden, South Holland, NetherlandsRecruiting

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Source record: clinicaltrials.gov/study/NCT06620705