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Study identifier: NCT06619990 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis

Condition: Ulcerative Colitis (UC)  ·  Sponsor: Xencor, Inc.

PhasePhase 1/Phase 2
Planned participants270
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersYes

About this study

The Phase 1 study described herein will evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of XmAb942 in healthy volunteers (Parts A and B). Part C of this study will be a Phase 2 study to evaluate XmAb942 in participants with ulcerative colitis (UC).

This description comes directly from the study's public registry record.

Talk to the study team

942 Study Information  ·  Xenith-UCinfo@xencor.com

Always discuss trial participation with your own doctor first.

Locations (90)

Xencor Investigative SiteScottsdale, Arizona, United StatesRecruiting
Xencor Investigative SiteBradenton, Florida, United StatesRecruiting
Xencor Investigative SiteBrandon, Florida, United StatesRecruiting
Xencor Investigative SiteJacksonville, Florida, United StatesRecruiting
Xencor Investigative SiteKissimmee, Florida, United StatesRecruiting
Xencor Investigative SiteMargate, Florida, United StatesRecruiting
Xencor Investigative SitePalmetto Bay, Florida, United StatesRecruiting
Xencor Investigative SiteTampa, Florida, United StatesRecruiting
Xencor Investigative SiteTampa, Florida, United StatesRecruiting
Xencor Investigative SiteLouisville, Kentucky, United StatesRecruiting
Xencor Investigative SiteOxford, Mississippi, United StatesRecruiting
Xencor Investigative SiteTupelo, Mississippi, United StatesRecruiting

+ 78 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06619990