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Study identifier: NCT06617923 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Study of Senaparib in Combination With Temozolomide in ARID1A Mutation Associated Ovarian Cancer

Condition: Ovary Cancer · Fallopian Tube Cancer · Primary Peritoneal Cavity Cancer  ·  Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

PhasePhase 2
Planned participants18
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a phase 2 study to test the effectiveness (anti-tumor activity) of the combination of the study drugs, Senaparib and Temozolomide, in patients with clear cell or endometrioid ovarian cancers that have ARID1A pathologic variants.

This description comes directly from the study's public registry record.

Talk to the study team

Hopkins GYN Trials  ·  410-614-1361  ·  HopkinsGynTrials@jhmi.edu

Sidney Kimmel Cancer Center Clinical Research Office  ·  410-955-8866  ·  jhcccro@jhmi.edu

Always discuss trial participation with your own doctor first.

Locations (2)

Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsBaltimore, Maryland, United StatesRecruiting
University of Pennsylvania/Abramson Cancer CenterPhiladelphia, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06617923