Condition: Respiratory Failure · Interstitial Lung Disease (ILD) · Pulmonary Fibrosis · Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)
Lung transplantation is a complex procedure performed in patients with terminal lung disease. The transplant procedure stresses the patient's heart and lungs, which are already taxed by the underlying disease process. The heart-lung machine is occasionally used to support the patient and ensure adequate oxygen supply to other organs during the operation. It can be used routinely in all patients or selectively in patients who exhibit reduced oxygen supply to the remaining organs. This process, known as cardiopulmonary bypass (CPB), pumps blood out of the body to a heart-lung machine that removes carbon dioxide and returns oxygen-filled blood to the body. Although using the CPB increases the risk of bleeding, infection, and coagulation complications, it should still be considered in high-risk patients to compensate for more severe complications such as kidney failure and stroke caused by a lack of cardiopulmonary support. Extracorporeal membrane oxygenation (ECMO) is a recently developed CPB variation associated with fewer bleeding complications. It has recently replaced the traditional heart-lung machine as the preferred method of cardiopulmonary support during lung transplantation. Since ECMO is associated with fewer complications than standard CPB, many centers have increased their use of ECMO during lung transplantation. Some have even employed it routinely. However, there remains significant debate on how often it should be used. Therefore, the study's main objective is …
This description comes directly from the study's public registry record.
Basil Nasir, MD · 514-890-8000 · basilsnasir@gmail.com
Alex Moore, MD · 514-890-8000 · alex.moore@umontreal.ca
Always discuss trial participation with your own doctor first.
| Univeristy of Alberta & Alberta Health Services | Edmonton, Alberta, Canada | Not Yet Recruiting |
| Vancouver General Hospital | Vancouver, British Columbia, Canada | Not Yet Recruiting |
| University Health Network / Toronto General Hospiatl | Toronto, Ontario, Canada | Not Yet Recruiting |
| Centre Hospitalier de l'Universite de Montreal | Montreal, Quebec, Canada | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06615492