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Study identifier: NCT06615102 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Reducing Cardiac-surgery Associated Acute Kidney Injury Occurence by Administering Angiotensin II

Condition: Cardiac Surgery · Vasoplegia  ·  Sponsor: Universität Münster

PhasePhase 3
Planned participants1022
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The study intervention focuses on exploring the use of angiotensin II as a primary vasopressor compared to norepinephrine in cardiac surgery patients to investigate whether angiotensin II can reduce the occurrence of moderate/severe acute kidney injury (AKI). Despite its potential, as suggested by trials involving surgical patients, there is currently no human data confirming its effectiveness in preventing moderate/severe AKI in this context. The intervention aims to address this gap by evaluating angiotensin II's impact compared to norepinephrine.

This description comes directly from the study's public registry record.

Talk to the study team

Alexander Zarbock, MD  ·  +49-251-8347252  ·  PAN-AKI@ukmuenster.de

Melanie Meersch-Dini, MD  ·  +49-251-8347255  ·  PAN-AKI@ukmuenster.de

Always discuss trial participation with your own doctor first.

Locations (4)

Deutsches Herzzentrum der CharitéBerlin, GermanyRecruiting
University Hospital BonnBonn, GermanyRecruiting
University Medical Center MainzMainz, GermanyRecruiting
University Hospital MünsterMünster, GermanyRecruiting

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Source record: clinicaltrials.gov/study/NCT06615102