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Study identifier: NCT06614270 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Anti-CD19 IL-10/IL15 CAR-NK Cells in Refractory/Relapsed Autoimmune Diseases

Condition: Systemic Sclerosis (SSc) · ANCA Associated Vasculitis (AAV) · Idiopathic Inflammatory Myopathy (IIM)  ·  Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University

PhaseNA
Planned participants15
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

This study is a single-center, open-label, single-arm, dose-escalation trial. The aim of this study is to investigate the safety and efficacy of Anti-CD19 IL-10/IL15 CAR-NK cells in patients with refractory/relapsed autoimmune diseases, including systemic lupus erythematosus, systemic sclerosis, idiopathic inflammatory myositis, ANCA associated vasculitis, sjogren syndrome, and antiphospholipid syndrome.

This description comes directly from the study's public registry record.

Talk to the study team

Jing Xue, MD.,  ·  +86-13758121751  ·  jingxue@zju.edu.cn

Always discuss trial participation with your own doctor first.

Locations (1)

the second affiliated hospital Zhejiang University School of MedicineHangzhou, Zhejiang, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06614270