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Study identifier: NCT06613178 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Intravenous Acetaminophen After Cardiac Surgery - Definitive Study

Condition: Post Operative Delirium · Post Operative Pain · Post-Op Complication  ·  Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre

PhasePhase 4
Planned participants1100
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Double blind, double dummy trial of the use of IV acetaminophen versus oral acetaminophen for the prevention of delirium after cardiac surgery. The underlying hypothesis is that better pain control and less use of narcotics will lead to a lower incidence of delirium from day 1 to 7 following cardiac surgery. Other important secondary outcomes are the total use of narcotics, ICU and hospital stay, improved cognitive function at 6 months and 1 year post surgery, NSAID use at each centre and associated NSAID complications.

This description comes directly from the study's public registry record.

Talk to the study team

Sheldon Magder, MD  ·  5149475918  ·  sheldon.magder@mcgill.ca

Always discuss trial participation with your own doctor first.

Locations (8)

University of British ColumbiaVancouver, British Columbia, CanadaActive Not Recruiting
University of ManitobaWinnipeg, Manitoba, CanadaRecruiting
Trillium Health CentreMississagua, Ontario, CanadaNot Yet Recruiting
University of OttawaOttawa, Ontario, CanadaNot Yet Recruiting
Sunnybroook Health CentreToronto, Ontario, CanadaNot Yet Recruiting
McGill Universtiy Health CentreMontreal, Quebec, CanadaRecruiting
Universite MontrealMontreal, Quebec, CanadaRecruiting
University of LavalQuébec, Quebec, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT06613178