Condition: Endoscopic Submucosal Dissection · Levobupivacaine · Sponsor: Laura Boer
Endoscopic submucosal dissection (ESD) is commonly performed for (pre)cancerous lesions in the esophagus. Following ESD, post-procedural chest pain is seen in many patients. Studies have shown that local bupivacaine (BP) into the residual submucosal layer of the resection wound after gastric ESD could reduce post-procedural pain rates effectively. Levobupivacaine (LB) is equipotent to BP regarding analgesic effects, but has a better safety profile. No studies have been performed to evaluate the efficacy of LB after esophageal ESD to reduce pain. Therefore, we want to evaluate the effect on post-procedural pain of local application of LB during esophageal ESD.
This description comes directly from the study's public registry record.
Laura S Boer, Degree of medicine · 0887550224 · l.boer1@antoniusziekenhuis.nl
Always discuss trial participation with your own doctor first.
| UMCG | Groningen, Netherlands | Recruiting |
| St Antonius Hospital | Nieuwegein, Netherlands | Recruiting |
| UMCU | Utrecht, Netherlands | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06611176