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Study identifier: NCT06610760 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Efficacy and Safety of Ursodeoxycholic Acid in Reversing Gastric Intestinal Metaplasia

Condition: Gastric Intestinal Metaplasia  ·  Sponsor: Yongquan Shi

PhasePhase 4
Planned participants196
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to investigate the efficacy of ursodeoxycholic acid in treating gastric intestinal metaplasia in Helicobacter pylori-negative adults. It will also learn about the safety of ursodeoxycholic acid. The main questions it aims to answer are: Does ursodeoxycholic acid promote the regression of IM in individuals without Helicobacter pylori infection? What medical problems do participants experience when taking ursodeoxycholic acid? Researchers will compare ursodeoxycholic acid to a placebo (a look-alike substance that contains no drug) to see if ursodeoxycholic acid is effective in treating gastric intestinal metaplasia. Participants will: Take ursodeoxycholic acid or a placebo every day for 6 months. Visit the clinic once every 4 weeks for checkups and tests.

This description comes directly from the study's public registry record.

Talk to the study team

Yongquan Shi  ·  0086 + 02984771515  ·  shiyquan@fmmu.edu.cn

Always discuss trial participation with your own doctor first.

Locations (6)

989 Hospital of PLA Joint Logistics Support ForcePingdingshan, Henan, ChinaRecruiting
Ankang Central HospitalAnkang, Shaanxi, ChinaRecruiting
Hanzhong 3201 HospitalHanzhong, Shaanxi, ChinaRecruiting
Shangluo Central HospitalShangluo, Shaanxi, ChinaRecruiting
Xijing hospitalXi'an, Shaanxi, ChinaRecruiting
Xi'an Central HospitalXi'an, Shaanxi, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06610760