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Study identifier: NCT06606730 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Personalizing the Use of Pembrolizumab for Patients Who Have a Strong Response in Early Triple Negative Breast Cancer

Condition: Breast Cancers · Triple Negative Breast Cancer (TNBC)  ·  Sponsor: UNICANCER

PhasePhase 3
Planned participants2454
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

OPT-PEMBRO trial is a pragmatic, multicentre, international, prospective, non-inferiority, two-arms, randomised (1:1), open-label, Phase III clinical study. The main goal of this research is to determine if patients with triple-negative breast cancer, who experience a complete response after neoadjuvant treatment, have the same chance of avoiding cancer recurrence whether they stop pembrolizumab or continue taking it for an additional 6 months. This research will also take into account patients tolerance to treatment and quality of life.

This description comes directly from the study's public registry record.

Talk to the study team

Sonia Mardinian  ·  +33 6 98 54 96 60  ·  s-mardinian@unicancer.fr

Always discuss trial participation with your own doctor first.

Locations (2)

Cliniques Universitaires Saint Luc BrusselsBrussels, BelgiumRecruiting
Institut Gustave RoussyVillejuif, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT06606730