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Study identifier: NCT06606327 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Diazoxide Suppression Test P&F Study

Condition: Insulin Resistance · Hyperinsulinemia · Obesity  ·  Sponsor: Columbia University

PhasePhase 1
Planned participants10
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

The goal of this study is to learn about how the hormone insulin controls blood sugar. The main question it aims to answer is about how much insulin the body actually needs to maintain a normal blood sugar level. People with obesity and high insulin levels will receive eight doses of diazoxide, a drug that suppresses the pancreas's production of insulin, and will have their fasting blood sugar and insulin levels checked daily while taking the drug.

This description comes directly from the study's public registry record.

Talk to the study team

Joshua R Cook, MD, PhD  ·  2123056289  ·  jrc2175@cumc.columbia.edu

Ishwari Nagnur  ·  2123059336  ·  imn2113@cumc.columbia.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Columbia University Irving Medical CenterNew York, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06606327