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Study identifier: NCT06606119 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

The Role of Brain-Bone Marrow-Gut Interaction Following Major Trauma

Condition: Trauma Injury · Trauma · Critical Illness  ·  Sponsor: University of Florida

PhaseN/A
Planned participants275
Who can joinAll sexes, 18 Years to 100 Years
Healthy volunteersNo

About this study

Traumatic injury followed by critical illness provokes pathophysiologic changes in the bone marrow and the gut that contribute to persistent anemia and changes in the microbiome which significantly impact long-term recovery. This project will define the interactions between the stress, chronic inflammation, bone marrow dysfunction, and an altered microbiome which will provide a strong foundation for future clinical interventions to help improve outcomes following severe trauma.

This description comes directly from the study's public registry record.

Talk to the study team

Ruth Davis, BSN  ·  352-273-8759  ·  ruth.davis@surgery.ufl.edu

Jennifer Lanz, MSN  ·  352-273-5497  ·  jennifer.lanz@surgery.ufl.edu

Always discuss trial participation with your own doctor first.

Locations (3)

UF Academic Research BuildingGainesville, Florida, United StatesRecruiting
UF Health at Shands HospitalGainesville, Florida, United StatesRecruiting
UF Laboratory of Inflammation Biology and Surgical Science and Shands Hospital at UFGainesville, Florida, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06606119