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Study identifier: NCT06605898 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Optimized Tailored Interventions in Metabolic and Lifestyle Outcomes (OPTIMAL)

Condition: Cognitive Change · Diet, Healthy · Metabolic Syndrome, Protection Against  ·  Sponsor: University of Illinois at Urbana-Champaign

PhaseNA
Planned participants72
Who can joinAll sexes, 45 Years to 64 Years
Healthy volunteersYes

About this study

The goal of this clinical trial is to learn if increasing adherence to a Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet pattern improves brain and heart health relative to a healthy control diet in middle-aged adults. Our research team will evaluate three different groups: the first group will be chosen using a predictive analytics model that predicts who will benefit most from the MIND diet, the second group will follow the MIND diet without being pre-selected, and the third group will eat a standard healthy diet to serve as a comparison. The main questions it aims to answer are: Does the MIND diet improve cognitive performance and heart health relative to a control diet? How does the health impact of the MIND diet in participants pre-identified through predictive analytics compare to those without such pre-selection? Which of the three groups - predictive analytics selected MIND diet group, standard MIND diet group, or healthy control - demonstrate the most significant improvements in cognitive and cardiovascular health over the course of the trial? Participants will: Consume one meal that follows the MIND diet or a control meal every day for 3 months. Visit the lab before and after the 3 months of meals for tests. Keep a record of the food they eat during the study.

This description comes directly from the study's public registry record.

Talk to the study team

Naiman Khan, PhD  ·  2173001667  ·  nakhan2@illinois.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Illinois at Urbana-ChampaignUrbana, Illinois, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06605898